OK - had a proper read through and I think I understand.
The problem you'll run into is most ad networks give you different ad tags for each site, so you would have to set up a different zone for each site within phpAdsNew, and then add the site-specific ad tags for each network for each zone in there.
Then just limit the pageviews per user/IP to 1 for each ad network and you should be ready to go.
Is that the sort of thing you are after? Let me know if you need some more specific info.